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John D. Clemens, M.D.
Director-General

John D. Clemens, M.D., Dr. John D. Clemens, Director General of the International Vaccine Institute (IVI), is an international expert on the evaluation of vaccines in developing countries. A graduate of Stanford (B.S.) and Yale (M.D.) Universities, Dr. Clemens is U.S.-Board Certified in Internal Medicine, and received his post-doctoral research training in clinical epidemiology at Yale. From 1983-88, he served as a research scientist at the International Centre for Diarrhoeal Disease Research, Bangladesh, where he led the first efficacy trial of an oral vaccine against cholera, and where he conducted additional research on measles vaccine. After returning to the U.S., he served as Chief of the Epidemiology Section of the Center for Vaccine Development of the University of Maryland, and then as Chief of the Epidemiology Branch of the National Institute of Child Health and Human Development , U.S. National Institutes of Health (NIH). While at NIH he was the Director of the first WHO Collaborating Centre for Vaccine Evaluation in Developing Countries and was a recipient of the NIH Director's Award for Outstanding Research on Vaccine Evaluation. In 1999 he became the first Director-General of the IVI, a position which he continues to hold. Dr. Clemens serves as an Adjunct Professor at the Seoul National University School of Public health.

In addition to field evaluations of vaccines, Dr Clemens' research has focused on innovative methodological approaches to evaluating vaccines in developing country populations, and to generating evidence needed for policy decisions about vaccine introduction in developing countries. He has conducted clinical studies of vaccines against cholera, enterotoxigenic Escherichia coli, typhoid fever, pneumococcus, tuberculosis, Haemophilus influenzae type b, measles, and Japanese encephalitis. His work in the developing world has included studies in Bangladesh, Chile, China, Egypt, India, Indonesia, Mozambique, Pakistan, Thailand, and Vietnam. He has published over 250 original, peer-reviewed articles, and serves on the editorial boards of several international journals. He is an elected member of the American Epidemiology Society and a Fellow of the American College of Epidemiology and of the Infectious Disease Society of America. Over the past 15 years he has served on several WHO Steering Committees, including committees for enteric vaccines, vaccine epidemiology, and vaccine safety, and he currently serves as a member of the Advisory Committee to the Director of the Initiative for Vaccine Research. He currently serves on the Board of the GAVI Alliance.

Michael Goon, MM
Deputy Director-General for Finance & Administration

Michael F. L. Goon, joined the Institute in January 2001 as its Deputy Director-General for Administration and Finance. He obtained a Masters in Management (MM) degree from the Asian Institute of Management Philippines. He is a Malaysian national, a Penang State Scholar at the University of Malaysia and a Fellow of the Institute of Directors, UK. Mr. Goon brings with him extensive management experience in both multinational profit organizations and international non-profit organizations. He has held very senior managerial positions in the corporate sector and has brought this vast commercial experience to help improve the organizational practices of the international non-profit world. Mr. Goon has worked in several countries in Malaysia, Singapore, the United Arab Emirates, Bangladesh, India, Philippines and the Ivory Coast. Mr. Goon had a highly successful track record in the corporate world. He grew in his career as a Cost Accountant rising to Chief Financial Accountant, Group Systems Manager, Deputy General Manager and then General Manager of large national and multi-national organizations. With the experiences acquired in the corporate sector, Mr. Goon embarked on a career in non-profit organizations to help build up and strengthen administrative, financial management and governance practices of international non-profit organizations to eventually become centers of excellence. He had worked at the International Center for Diarrhoeal Disease Research, Bangladesh (ICDDR,B) as its Associate Director for Administration and Finance, then joined the agricultural research centers in the Consultative Group for International Agricultural Research (CGIAR) and held positions of Assistant Director General for Administration and Finance at the International Crops Research Institute for Semi-Arid Tropics (ICRISAT), India; Deputy Director General Administration and Finance for the International Rice Research Institute (IRRI), Philippines; and Deputy Director General for Administration and Finance for the West Africa Rice Development Association (WARDA), Ivory Coast, West Africa .

Luis Jódar, Ph.D.
Deputy Director-General

Luis Jódar, Ph.D., joined the International Vaccine Institute in 2002 in Seoul, Korea, a non-profit international governmental organization established by the United Nations in 1997 to promote the health of children in developing countries through the development, introduction and use of new vaccines. At the IVI, he is responsible for directing the IVIĄ¯s Translational Research Division which conducts major programs of interdisciplinary research, clinical trials, data synthesis, and policy analyses on vaccines against cholera, typhoid fever, shigellosis, rotavirus, Japanese encephalitis, Haemophilus influenzae b, and Streptococcus pneumoniae. He is also responsible for developing new opportunities for strengthening IVIĄ¯s capacities in the vaccine continuum and establishing partnerships for product development and technology transfer with local and international manufacturers. Previously, he was with the World Health Organization (WHO) for six years in charge of meningococcal vaccines and quality and safety of vaccines against encapsulated bacteria. In this capacity, he provided scientific leadership, coordination and technical supervision of the WHO agenda on the development, clinical evaluation, licensing and introduction of new vaccines against meningococci. Prior to joining the WHO, he worked at the European Commission in Brussels as the scientific focal point of the Task Force for Vaccines and Viral Diseases. Before joining the EU, he was a post-doctoral fellow at the Departments of Neuroimmunology at Osaka and Nagasaki Universities in Japan. He received his B.Sc. with Honors in Pharmaceutical Sciences from the University of Madrid, Spain and his Ph.D. from the Physiopathology Department at the University of Madrid, Spain.

Dr. Jodar has served on a number of advisory groups to WHO, the EU, vaccine manufacturers and governments. He has a long track-record in launching and coordinating public private partnerships involving large alliances of vaccine producers, international organizations, academic institutions, government research laboratories, and ministries of health to accelerate vaccine development and introduction in developing countries including the Meningitis Vaccine Program, the Diseases of the Most Impoverished Program and the Cholera Vaccine Initiative.

Cecil Czerkinsky, Ph.D.
Deputy Director-General for Laboratory Sciences

Dr. Cecil Czerkinsky, a French immunologist, joined the International Vaccine Institute as the Deputy Director-General for Laboratory Sciences in October 2005.
Before joining the IVI, Dr. Czerkinsky has been serving as the Director of the Division of Mucosal Immunology and Vaccinology at INSERM (French National Institute of Health and Medical Research) since 1997, focusing on vaccine research and discovery of the basic mechanisms governing induction of immunity in mucosal organs.
Dr. Czerkinsky received doctoral degrees from the University of Lyon Odontology Faculty in France, and the University of Gothenburg in Sweden where he served as a professor of the immunology. He has more than 130 scientific peer-reviewed publications in immunology and vaccinology.
Dr. Czerkinsky invented the ELISPOT, a method for monitoring immune responses in humans and animals, which is used in laboratories world-wide. His work has been focused on basic immunological mechanisms pertaining to vaccine development against infections, auto-immune disorders and allergies. Dr. Czerkinsky holds several patents in these areas.
He is a co-founder of several biotechnology companies, including Maxim Pharmaceuticals Inc., a U.S. biopharmaceutical firm devoted to the development of therapeutic drugs for cancer and liver diseases.

Harold Margolis, M.D.
Deputy Director-General of IVI for PDVI Program

Harold Margolis, M.D. Harold S. Margolis, MD, is Director of the Pediatric Dengue Vaccine Initiative, a program of the International Vaccine Institute. He recently retired from the Centers for Disease Control and Prevention where he became an Epidemic Intelligence Service (EIS) Officer in 1975. At CDC, he directed viral hepatitis research and prevention activities from 1987 to 2004, and was Director of a World Health Organization Collaborating Center for Research and Reference in Viral Hepatitis. During 2001-2002 he was CDC's Senior Advisor for Smallpox Preparedness and Response.

Dr. Margolis is a pediatrician and a fellow of the American Academy of Pediatrics. His research and public health interests have focused on evaluation and introduction of new vaccines, molecular epidemiology, and the development of evidenced-based public health policy. He is the author or co-author of over180 peer reviewed publications.