Efforts to expand cholera vaccine use more extensively in the public health arena are advancing in the wake of a major vaccine trial in India recently. Cholera, an enteric infection, still kills an estimated 120,000 persons in the least developed countries each year. While provision of safe water and food, adequate sanitation, and improved hygiene are the major public health interventions to fight cholera, a safe, effective and affordable vaccine continues to be a potentially useful tool for cholera prevention and control. The IVI...